KYOWA KIRIN INTERNATIONAL PLC
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Next accounts due
2026-06-30 (in 1mo)
Last filed for 2024-12-31
Confirmation statement due
2026-08-11 (in 3mo)
Last made up 2025-07-28
Watchouts
Cash
£4M
-99.5% vs 2023
Net assets
£783M
-34% vs 2023
Employees
89
-6.3% vs 2023
Profit before tax
-£39M
-104.1% vs 2023
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
3 officer resignations in last 12 months
Multiple officers have left the board recently — see the People section for who.
Name history
Renamed 3 times since incorporation
- KYOWA KIRIN INTERNATIONAL PLC 2016-02-22 → present
- PROSTRAKAN GROUP PLC 2005-03-02 → 2016-02-22
- PROSTRAKAN GROUP LIMITED 2004-10-12 → 2005-03-02
- STRAKAN GROUP LIMITED 1999-08-10 → 2004-10-12
Net assets
2-year trend · vs Industrials median
Accounts
2-year trend · latest reflected 2024-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Turnover | — | — | |
| Operating profit | £92,600,000 | -£21,300,000 | |
| Profit before tax | £953,000,000 | -£38,800,000 | |
| Net profit | £948,300,000 | -£43,300,000 | |
| Cash | £737,000,000 | £3,600,000 | |
| Total assets less current liabilities | £1,190,700,000 | £817,600,000 | |
| Net assets | £1,186,300,000 | £783,000,000 | |
| Equity | £1,186,300,000 | £783,000,000 | |
| Average employees | 95 | 89 | |
| Wages | £10,700,000 | £14,400,000 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Return on capital employed | 7.8% | -2.6% | |
| Gearing (liabilities / total assets) | 32.0% | 53.0% | |
| Current ratio | 2.20x | 0.98x | |
| Interest cover | 2.83x | -0.94x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- FRS 101 Reduced Disclosure Framework
- Reporting scope
- Standalone (parent only)
- Auditor
- KPMG LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“The financial statements have been prepared on a going concern basis which the directors consider to be appropriate. The KKI Group has had a balance due from its parent, KKC, at 31 December 2024 of £283m. The Directors are satisfied that the KKI Group would be able to drawdown any funding required.”
Group structure
- KYOWA KIRIN INTERNATIONAL PLC · parent
- Kyowa Kirin Holdings B.V. 100%
- Kyowa Kirin Pharmaceuticals International Limited 100%
- Kyowa Kirin Ltd* 100%
- Kyowa Kirin Pharma SAS* 100%
- Kyowa Kirin Farmaceutica S.L.U.* 100%
- Kyowa Kirin GmbH* 100%
- Kyowa Kirin Pharma B.V.* 100%
- Kyowa Kirin S.r.l.* 100%
- Kyowa Kirin AB* 100%
- Kyowa Kirin Services Ltd 100%
- Kyowa Kirin Austria GmbH* 100%
- Kyowa Kirin Pharma S.r.o.* 100%
- Kyowa Kirin Ireland Ltd* 100%
- Kyowa Kirin S.a.r.l.* 100%
- Kyowa Kirin Farmaceutica, Unipessoal 100%
- Kyowa Kirin Pharma FZ LLC* 100%
- Orchard Therapeutics North America* 100%
- Orchard Therapeutics Netherlands B.V.* 100%
- Orchard Therapeutics (Italy) S.r.l* 100%
- Orchard Therapeutics (France) SAS* 100%
- Orchard Therapeutics (Germany) GmbH* 100%
- Orchard Therapeutics (Switzerland) GmbH* 100%
- Orchard Therapeutics (Sweden) AB* 100%
- Kyowa Kirin International HoldCo Ltd 100%
- Kyowa Kirin International UK HoldCo Ltd 100%
- Kyowa Kirin International HoldCo Scotland 49%
- Kyowa Kirin International NewCo France 49%
- Kyowa Kirin International NewCo Germany 49%
- Kyowa Kirin International NewCo Spain 49%
- Kyowa Kirin International NewCo Italy 49%
Significant events
- “Operating loss for the year ended 31 December 2024 was £21.3m (2023: profit of £92.6m) with a loss on ordinary activities after taxation of £43.3m (2023: profit of £948.3m).”
- “On 5 October 2023, Kyowa Kirin Co Ltd announced the intended acquisition by KKI of Orchard Therapeutics in a deal worth $397.4m to develop several biopharmaceutical candidates in areas including oncology and autoimmune diseases. The Company successfully completed the acquisition of Orchard Therapeutics on January 24, 2024.”
- “Under the terms of the agreement, Kyowa Kirin acquired all outstanding shares of Orchard Therapeutics at a price of $16.00. Additionally, there was a contingent value right (CVR) of $1.00 per ADS, payable upon the U.S. approval of OTL-200, a gene therapy for metachromatic leukodystrophy (MLD).”
- “The US approval completed in May in 2024 resulting in consideration of $287.9m for normal stock and $20.5m for contingent value rights, resulting in total consideration of $308.5m.”
- “On 24 November 2022, the KKI Group, of which Kyowa Kirin International plc is the immediate parent company of, announced a 'Joint Venture Collaboration' ('JVC') with Grünenthal GmbH for the established medicines portfolio. The JVC includes a portfolio of brands across six therapeutic areas, with revenues primarily resulting from pain management medicines. The deal completed on 1 August 2023.”
- “In 2026, KKI has the option to dispose of its minority stake in the JVC, and sell the underlying IP.”
- “An interim dividend of £360.0m was paid during the year (2023: £nil).”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
7 active · 51 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| REISINGER, Roswitha | Secretary | 2020-03-24 | — | — |
| ARISTIDOU, Antrinkos Andrew | Director | 2020-12-01 | Jun 1968 | British |
| CARTER, Paul Rutherford | Director | 2023-04-01 | Jul 1960 | British |
| DE CRAECKER, Françoise Marie | Director | 2024-04-01 | Dec 1961 | Belgian |
| DEHAENE-PUYPE, Julie Helene Madeleine | Director | 2025-11-03 | Apr 1973 | French |
| KUNII, Daisuke | Director | 2024-01-19 | Mar 1978 | Japanese |
| OKA, Yoshiko | Director | 2026-03-19 | Feb 1970 | Japanese |
Show 51 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| MCLEAN, Andrew Firth | Secretary | 2000-01-20 | 2020-03-24 |
| WILL, James Robert | Secretary | 1999-08-10 | 2000-01-20 |
| ALLEN, Peter Vance | Director | 2005-01-01 | 2013-12-18 |
| ASBURY, Michael John, Dr | Director | 2005-03-02 | 2013-12-18 |
| BARON, Roland, Professor | Director | 2004-09-15 | 2005-12-29 |
| BENNETT, Michael Andrew | Director | 2000-02-16 | 2006-05-10 |
| BLAKE, Walter | Director | 1999-08-10 | 2000-01-20 |
| BROWN, John Robert, Dr | Director | 2014-01-01 | 2017-04-01 |
| CAWDRON, Peter Edward Blackburn | Director | 2005-07-01 | 2011-04-21 |
| CHRISTIANSEN, Claus Henrik | Director | 2000-01-20 | 2001-12-19 |
| COOK, James | Director | 2000-02-16 | 2001-06-30 |
| DOI, Kyosuke | Director | 2014-09-10 | 2019-01-28 |
| EBSWORTH, David Raymond, Dr | Director | 2017-04-01 | 2024-04-01 |
| FILDES, Francis James Thomas, Dr | Director | 2003-01-30 | 2011-04-21 |
| FILLIAS, George Gaspard | Director | 2004-12-08 | 2005-03-18 |
| FRASER, Andrew John | Director | 2004-09-15 | 2005-03-23 |
| FUJII, Hirohisa | Director | 2020-03-24 | 2023-12-31 |
| FUJII, Yasuo | Director | 2015-09-23 | 2016-09-20 |
| FUJII, Yasuo | Director | 2012-09-12 | 2014-09-10 |
| FURUYA, Yoshihiro | Director | 2020-03-24 | 2024-04-01 |
| GARDNER, Adrian David Edmund | Director | 2002-05-23 | 2007-06-29 |
| GARVEY, Paul Maurice | Director | 2007-04-16 | 2009-08-11 |
| GOODMAN, Jonathan Ross | Director | 2011-01-12 | 2011-05-17 |
| GRANATA, Francesco, Dr | Director | 2017-04-01 | 2023-03-31 |
| GRAY, Derek Richard | Director | 2000-01-20 | 2001-12-19 |
| ISHIDA, Hiroshi | Director | 2024-04-01 | 2026-03-31 |
| JENKINS, William John, Dr | Director | 2001-04-25 | 2005-03-23 |
| KANIS, John Anthony, Professor | Director | 2000-01-20 | 2005-03-23 |
| KENT, Ian Fletcher | Director | 2000-02-16 | 2000-05-31 |
| LABBE, Jean-Francois | Director | 2004-03-10 | 2005-01-31 |
| LOWCOCK, Nicholas | Director | 2001-04-25 | 2007-06-25 |
| MIKAYAMA, Toshifumi, Dr | Director | 2012-03-07 | 2023-03-24 |
| MOELLER, Gerald Heinz, Dr | Director | 2000-08-18 | 2002-03-21 |
| MORGAN, Jeremy Lewis | Director | 2023-01-03 | 2025-11-03 |
| MULLICK, Abdul Hafeez, Dr | Director | 2023-03-24 | 2025-03-19 |
| MULLICK, Abdul Hafeez | Director | 2019-01-28 | 2023-01-03 |
| O'SHEA, William James | Director | 2014-01-01 | 2017-04-01 |
| REDMOND, Michael | Director | 2001-07-17 | 2004-07-08 |
| STRATFORD, Harry Thomas, Dr | Director | 2011-07-07 | 2019-01-28 |
| STRATFORD, Harry Thomas | Director | 2000-01-20 | 2007-12-06 |
| SUDA, Toshio | Director | 2019-01-28 | 2020-03-24 |
| SUDO, Tomohiro | Director | 2025-03-19 | 2026-03-19 |
| SUDO, Tomohiro | Director | 2016-12-16 | 2020-03-24 |
| TACHIBANA, Kazuyoshi | Director | 2011-04-21 | 2012-03-07 |
| TOTTEN, Wilson, Dr | Director | 2004-09-15 | 2010-09-06 |
| TURTON, Simon, Dr | Director | 2007-06-25 | 2011-04-21 |
| TURTON, Simon, Dr | Director | 2004-09-15 | 2005-03-22 |
| WALKER, Alan Keith | Director | 2006-01-24 | 2008-01-28 |
| WATSON, Allan Mark | Director | 2009-09-09 | 2020-03-24 |
| WILL, James Robert | Nominee Director | 1999-08-10 | 2000-01-20 |
| YAMASHITA, Yoshinori | Director | 2011-04-21 | 2012-09-12 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Kyowa Kirin Co., Ltd. | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2016-04-06 | Active |
Filing timeline
Last 20 of 394 total filings
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-01 | AP01 | officers | Appoint person director company with name date | |
| 2026-04-01 | TM01 | officers | Termination director company with name termination date | |
| 2026-03-20 | TM01 | officers | Termination director company with name termination date | |
| 2025-11-06 | AP01 | officers | Appoint person director company with name date | |
| 2025-11-03 | TM01 | officers | Termination director company with name termination date | |
| 2025-09-01 | CH01 | officers | Change person director company with change date | |
| 2025-08-22 | CH01 | officers | Change person director company with change date | |
| 2025-08-01 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-07-01 | AA | accounts | Accounts with accounts type full | |
| 2025-03-26 | AP01 | officers | Appoint person director company with name date | |
| 2025-03-25 | TM01 | officers | Termination director company with name termination date | |
| 2024-08-06 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-07-02 | AA | accounts | Accounts with accounts type full | |
| 2024-04-12 | AP01 | officers | Appoint person director company with name date | |
| 2024-04-12 | TM01 | officers | Termination director company with name termination date | |
| 2024-04-05 | AP01 | officers | Appoint person director company with name date | |
| 2024-04-05 | TM01 | officers | Termination director company with name termination date | |
| 2024-01-22 | AP01 | officers | Appoint person director company with name date | |
| 2024-01-03 | TM01 | officers | Termination director company with name termination date | |
| 2023-08-07 | CS01 | confirmation-statement | Confirmation statement with no updates |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 9
- Capital events
- 0
- Officers appointed
- 2
- Officers resigned
- 3
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.
Year-on-year
FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31
-
Turnover
—
Not reported
-
Cash
-99.5%
£737,000,000 £3,600,000
-
Net assets
-34%
£1,186,300,000 £783,000,000
-
Employees
-6.3%
95 89
-
Operating profit
-123%
£92,600,000 -£21,300,000
-
Profit before tax
-104.1%
£953,000,000 -£38,800,000
-
Wages
+34.6%
£10,700,000 £14,400,000
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers