AVIADOBIO LTD
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Next accounts due
2026-09-30 (in 4mo)
Last filed for 2024-12-31
Confirmation statement due
2027-01-02 (in 8mo)
Last made up 2025-12-19
Watchouts
None on the register
Cash
£47M
+67.4% vs 2023
Net assets
£36M
+18.6% vs 2023
Employees
65
+1.6% vs 2023
Profit before tax
-£22M
+2.8% vs 2023
Name history
Renamed 1 time since incorporation
- AVIADOBIO LTD 2021-12-02 → present
- NEUROGENEUS LTD 2019-12-20 → 2021-12-02
Net assets
2-year trend · vs Health Care median
Accounts
2-year trend · latest reflected 2024-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Turnover | — | £2,371,625 | |
| Operating profit | -£22,725,259 | -£22,302,835 | |
| Profit before tax | -£22,315,481 | -£21,684,439 | |
| Net profit | -£19,119,174 | -£18,104,401 | |
| Cash | £28,188,800 | £47,190,003 | |
| Total assets less current liabilities | £30,586,307 | £41,964,442 | |
| Net assets | £30,586,307 | £36,277,183 | |
| Equity | £30,586,307 | £36,277,183 | |
| Average employees | 64 | 65 | |
| Wages | £8,289,148 | £8,724,844 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Operating margin | — | -940.4% | |
| Net margin | — | -763.4% | |
| Return on capital employed | -74.3% | -53.1% | |
| Gearing (liabilities / total assets) | 11.2% | 37.7% | |
| Current ratio | 8.52x | 3.24x | |
| Interest cover | -1955.03x | -116.15x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Consolidated group
- Auditor
- BDO LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“In preparing the financial statements, the directors have assessed the ability of the company and its subsidiary undertakings (collectively "the group") to continue as a going concern for a period of at least 12 months from the date of approval of these financial statements. This assessment included detailed review of cash flow forecasts and funding arrangements. The group is currently in a research and development phase, which has resulted in an operating loss for the period. Consistent with the group's lifecycle stage, it continues to operate with net cash outflows, however, licensing income is now being recognised.”
Group structure
- AVIADOBIO LTD · parent
- Neurogeneus Ltd 100%
- AviadoBio Inc. 100%
Significant events
- “During the year the company had continued to advance its portfolio of gene therapies for neurodegenerative diseases. This had included the continued dosing of patients in ASPIRE-FTD a Phase 1/2 human clinical trial that had evaluated AVB-101 in Frontotemporal dementia patients, and the presentation of early clinical experience data at a scientific forum in late 2024.”
- “The company successfully raised $61,200,000 in funding through two key transactions.”
- “In April 2025, as part of the strategic partnership with Astellas Pharma Inc., the Second Option Upfront Payment of $10,000,000 was received.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
9 active · 4 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BARKER, Laurence Daniel Paul | Director | 2020-09-11 | Jun 1972 | British |
| DESCHAMPS, Lisa | Director | 2021-11-22 | Apr 1971 | American |
| FUNNELL, Timothy Michael, Dr | Director | 2021-11-26 | Oct 1986 | British |
| GOATER, James Jeffrey | Director | 2023-02-01 | Aug 1975 | American |
| LOPEZ, Julio Cesar | Director | 2026-03-20 | Sep 1990 | American |
| MACLAUGHLIN, Fiona Caroline, Dr | Director | 2022-08-26 | Apr 1971 | British |
| SALZMAN, Amber | Director | 2021-09-06 | Nov 1961 | American |
| SCHMIDT, Dominic, Dr | Director | 2022-09-01 | Feb 1982 | British,German |
| SINHA, Nihal | Director | 2020-09-11 | Aug 1984 | British |
Show 4 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| BOLGER, Jeanne Elizabeth, Dr | Director | 2020-09-11 | 2022-08-26 |
| MALIK, Shahzad | Director | 2020-09-11 | 2022-09-01 |
| MCAVINEY, Matthew Douglas | Director | 2021-11-23 | 2026-03-20 |
| SHAW, Christopher Edward Dennistoun | Director | 2019-12-20 | 2020-09-11 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Kings College London | Corporate entity | Shares 25–50%, Voting 25–50% | 2020-09-11 | Ceased 2021-12-03 |
| Lifearc | Corporate entity | Significant influence | 2020-09-11 | Ceased 2021-12-03 |
| Dementia Discovery General Partner Llp | Corporate entity | Significant influence | 2020-09-11 | Ceased 2021-12-03 |
| Advent Life Sciences Llp | Corporate entity | Significant influence | 2020-09-11 | Ceased 2021-12-03 |
| Johnson & Johnson | Corporate entity | Significant influence | 2020-09-11 | Ceased 2021-12-03 |
| Christopher Edward Dennistoun Shaw | Individual | Shares 50–75%, Voting 50–75% | 2019-12-20 | Ceased 2020-09-11 |
Filing timeline
Last 20 of 91 total filings
Material constitutional events — rename, articles re-file, resolution
- 2026-04-24 RESOLUTIONS Resolution
- 2025-09-02 RP04SH01 Legacy PDF
- 2024-10-27 MA Memorandum articles
- 2024-10-27 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-24 | RESOLUTIONS | resolution | Resolution | |
| 2026-04-21 | SH01 | capital | Capital allotment shares | |
| 2026-04-08 | SH01 | capital | Capital allotment shares | |
| 2026-04-01 | TM01 | officers | Termination director company with name termination date | |
| 2026-04-01 | AP01 | officers | Appoint person director company with name date | |
| 2026-02-25 | SH01 | capital | Capital allotment shares | |
| 2025-12-19 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-11-27 | SH01 | capital | Capital allotment shares | |
| 2025-09-02 | RP04SH01 | change-of-name | Legacy | |
| 2025-08-28 | SH01 | capital | Capital allotment shares | |
| 2025-07-31 | AA | accounts | Accounts with accounts type group | |
| 2025-06-19 | SH01 | capital | Capital allotment shares | |
| 2025-05-13 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2024-12-30 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2024-11-29 | AA | accounts | Accounts with accounts type small | |
| 2024-11-04 | SH01 | capital | Capital allotment shares | |
| 2024-10-27 | MA | incorporation | Memorandum articles | |
| 2024-10-27 | RESOLUTIONS | resolution | Resolution | |
| 2024-08-15 | RP04SH01 | capital | Second filing capital allotment shares | |
| 2024-08-14 | RP04SH01 | capital | Second filing capital allotment shares |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 13
- Capital events
- 9
- Officers appointed
- 1
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.
Year-on-year
FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31
-
Turnover
—
Not reported
-
Cash
+67.4%
£28,188,800 £47,190,003
-
Net assets
+18.6%
£30,586,307 £36,277,183
-
Employees
+1.6%
64 65
-
Operating profit
+1.9%
-£22,725,259 -£22,302,835
-
Profit before tax
+2.8%
-£22,315,481 -£21,684,439
-
Wages
+5.3%
£8,289,148 £8,724,844
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers