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Next accounts due

2026-09-30 (in 4mo)

Last filed for 2024-12-31

Confirmation statement due

2026-05-12

Overdue

Watchouts

1 item

Cash

£60M

-43.3% vs 2023

Net assets

£79M

+1% vs 2023

Employees

146

+5.8% vs 2023

Profit before tax

-£5M

+86.8% vs 2023

Watchouts

Facts from the Companies House register and the latest accounts — not a rating

Accounts

2-year trend · latest reflected 2024-12-31

Metric Trend 2023-12-312024-12-31
Turnover £9,159,923£43,826,699
Operating profit -£40,019,645-£8,109,055
Profit before tax -£37,259,282-£4,936,564
Net profit -£33,269,738-£2,505,629
Cash £106,723,692£60,473,632
Total assets less current liabilities £100,336,259£78,623,604
Net assets £77,814,077£78,585,429
Equity £77,814,077£78,585,429
Average employees 138146
Wages £9,248,824£9,055,424

Values shown as filed in the company's annual accounts. indicates the figure wasn't present under that line item in that period. About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2023-12-312024-12-31
Operating margin -436.9%-18.5%
Net margin -363.2%-5.7%
Return on capital employed -39.9%-10.3%
Current ratio 5.25x7.11x

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.

Audit & accounting basis

Accounting basis
FRS 102
Reporting scope
Standalone (parent only)
Auditor
KPMG LLP
Audit opinion
Unqualified (clean)
Going concern
Affirmed

“The directors have prepared the financial statements on the going concern basis as they do not intend to liquidate the Company or to cease its operations, and as they have concluded that the Company's financial position means that this is realistic. They have also concluded that there are no material uncertainties that could have cast significant doubt over its ability to continue as a going concern for at least a year from the date of approval of the financial statements ('the going concern period').”

Significant events

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

9 active · 6 resigned

Name Role Appointed Born Nationality
BESHAR, Luke Matthew Director 2024-07-24 May 1958 American
BINGHAM, Catherine Elizabeth, Dame Director 2023-07-28 Oct 1965 British
CLANCY, Annette Director 2025-06-13 Nov 1954 British
LECHLER, Robert, Sir Director 2020-06-02 Dec 1951 British
LONG-MCGIE, Jeffrey Stephen Director 2021-11-24 Feb 1976 American
MCGILL, Iain Director 2020-01-01 May 1972 British
PATEL, Dhavalkumar D, Dr Director 2020-06-02 Aug 1961 American
PETRIS, Elisa Michela, Dr Director 2019-03-19 Jan 1979 Italian,Canadian
RIVERS, Tyrell Jermaine Director 2023-06-02 Nov 1972 American
Show 6 resigned officers
Name Role Appointed Resigned
MITRE SECRETARIES LIMITED Corporate Secretary 2019-03-19 2024-03-08
ASHRAFIAN, Houman, Professor Director 2021-11-24 2023-08-15
FUEYO, Alberto Sanchez, Professor Director 2019-03-29 2021-11-24
MEARS, Rachel Brooke Director 2021-11-24 2025-05-31
MURPHY, Martin Patrick, Dr Director 2019-03-19 2023-12-31
RHIND, Stephen Keith Director 2019-03-29 2021-02-28

Ownership

Persons with significant control

Name Kind Nature of control Notified Status
Syncona Portfolio Limited Corporate entity Shares 50–75%, Voting 50–75% 2019-03-29 Ceased 2019-03-29
Syncona Limited Corporate entity Shares 25–50%, Voting 25–50% 2019-03-29 Active

Filing timeline

Last 20 of 84 total filings

Date Type Category Description
2026-05-11 CH01 officers Change person director company with change date PDF
2026-05-11 CH01 officers Change person director company with change date PDF
2026-04-21 SH01 capital Capital allotment shares PDF
2025-12-15 SH06 capital Capital cancellation shares
2025-12-15 SH03 capital Capital return purchase own shares
2025-12-15 SH03 capital Capital return purchase own shares
2025-11-19 SH06 capital Capital cancellation shares
2025-10-01 SH08 capital Capital name of class of shares
2025-09-30 SH10 capital Capital variation of rights attached to shares
2025-09-01 RP04AP01 officers Second filing of director appointment with name PDF
2025-08-29 AP01 officers Appoint person director company with name date
2025-07-23 AA accounts Accounts with accounts type full
2025-06-27 AP01 officers Appoint person director company with name date PDF
2025-06-26 TM01 officers Termination director company with name termination date PDF
2025-06-06 SH01 capital Capital allotment shares
2025-06-02 CS01 confirmation-statement Confirmation statement with updates PDF
2024-10-12 AA accounts Accounts with accounts type full
2024-05-16 CS01 confirmation-statement Confirmation statement with updates PDF
2024-05-16 CH01 officers Change person director company with change date PDF
2024-05-14 CH01 officers Change person director company with change date PDF

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
16

last 12 months

Capital events
8

last 24 months

Officers appointed
1

last 12 months

Officers resigned
1

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Year-on-year

FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31

Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers

Official Companies House page