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Next accounts due

2026-09-30 (in 4mo)

Last filed for 2024-12-31

Confirmation statement due

2027-02-16 (in 9mo)

Last made up 2026-02-02

Watchouts

3 items

Cash

£13M

-22.9% vs 2023

Net assets

£11M

+10,428.5% vs 2023

Employees

30

-58.3% vs 2023

Profit before tax

-£2M

+81.8% vs 2023

Watchouts

Facts from the Companies House register and the latest accounts — not a rating

Name history

Renamed 2 times since incorporation

  1. AKAMIS BIO LIMITED 2023-01-03 → present
  2. PSIOXUS THERAPEUTICS LIMITED 2011-01-05 → 2023-01-03
  3. MYOTEC THERAPEUTICS LTD. 2006-11-17 → 2011-01-05

Accounts

2-year trend · latest reflected 2024-12-31

Metric Trend 2023-12-312024-12-31
Turnover £1,041,795£13,306,610
Operating profit -£23,766,025-£2,039,420
Profit before tax -£9,097,934-£1,652,478
Net profit -£6,829,138-£1,130,058
Cash £17,349,455£13,378,519
Total assets less current liabilities £15,146,812£21,453,754
Net assets £101,377£10,673,480
Equity £101,377£10,673,480
Average employees 7230
Wages £6,764,483£3,863,748

Values shown as filed in the company's annual accounts. indicates the figure wasn't present under that line item in that period. About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2023-12-312024-12-31
Operating margin -2281.3%-15.3%
Net margin -655.5%-8.5%
Return on capital employed -156.9%-9.5%
Gearing (liabilities / total assets) 99.6%63.0%
Current ratio 2.42x3.77x
Interest cover -376.63x-45.10x

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.

Audit & accounting basis

Accounting basis
IFRS
Reporting scope
Consolidated group
Auditor
PricewaterhouseCoopers LLP
Audit opinion
Unqualified (clean)
Going concern
Material uncertainty disclosed

“These circumstances represent a material uncertainty which may cast significant doubt on the group's and company's ability to continue as a going concern. Therefore, the group and company may be unable to realise their assets and discharge their liabilities in the normal course of business.”

Group structure

  1. AKAMIS BIO LIMITED · parent
    1. Hybrid Biosystems Limited 100% · England · was dormant
    2. AkaBio US LegacyCo, Inc. 100% · USA · research and development

Significant events

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

2 active · 36 resigned

Name Role Appointed Born Nationality
OAKWOOD CORPORATE SECRETARY LIMITED Corporate Secretary 2023-07-10
DAVIS JR, Howard E Director 2022-07-01 May 1973 American
Show 36 resigned officers
Name Role Appointed Resigned
CAVALLA, David John, Dr Secretary 2007-09-23 2008-04-23
HAROLD, Theodora Secretary 2008-04-23 2016-10-04
KENNEDY, Madeleine Secretary 2016-10-04 2018-02-01
MANDE, Priya Secretary 2018-02-01 2022-10-28
RAYNER, William Secretary 2006-11-17 2007-09-24
AGGER, Mette Kirstine Director 2012-07-06 2017-11-30
AGGER, Mette Kristine Director 2012-07-06 2023-06-30
BACH, Daniel Director 2018-02-01 2018-04-30
BEADLE, John William, Dr Director 2009-05-21 2021-12-31
BHAMAN, Maina Director 2010-04-09 2017-11-30
BOWDEN, Christopher, Dr Director 2024-10-28 2025-11-12
BOWDEN, Christopher, Dr Director 2023-06-01 2024-10-17
BRAGMAN, Keith Stephen, Dr Director 2007-09-24 2009-01-16
CAVALLA, David John, Dr Director 2007-09-23 2008-10-06
CHAN, Adrian Kin Fei Director 2024-10-17 2025-11-12
COATS, Andrew Justin Stewart, Professor Director 2007-09-24 2010-12-15
COHEN, Ezra, Dr Director 2020-07-01 2023-09-30
FOY, Matthew Director 2012-07-06 2024-10-17
GARRAWAY, Richard, Dr Director 2006-11-17 2008-01-23
GREDSTED, Lars Director 2023-06-30 2024-10-17
HARRIS, Ralph Stephen Director 2008-04-23 2009-02-20
HIGGONS, J. Duncan Director 2017-09-27 2024-10-17
KERR, Simon Christopher Director 2009-03-16 2011-01-28
L'HUILLIER, Phillip John, Dr Director 2010-12-15 2012-07-06
LINCOLN, Robin Lewis Director 2021-02-24 2024-10-17
MANDE, Priya Director 2016-09-29 2022-09-12
MOORE, Michael, Dr Director 2009-05-21 2017-11-30
PAOLETTI, Paolo, Dr Director 2011-11-23 2023-06-30
POOLE WILSON, Philip, Professor Director 2007-09-23 2009-01-16
ROWLAND JR, Charles Director 2017-09-27 2017-11-30
ROWLAND JR, Charles Director 2017-09-27 2019-10-30
SHEN, Richard Nan Director 2024-10-17 2025-11-12
SWINGLAND, Charles Stuart Webb Director 2010-10-04 2017-11-30
IP2IPO SERVICES LIMITED Corporate Director 2018-04-30 2024-10-17
IP2IPO SERVICES LIMITED Corporate Director 2018-04-30 2018-04-30
MERCIA FUND MANAGEMENT (NOMINEES) LIMITED Corporate Director 2010-12-15 2012-07-06

Ownership

Persons with significant control

Name Kind Nature of control Notified Status
Mr Howard E Davis Jr Individual Appoints directors 2025-11-12 Active
Dr Fengsheng Che Individual Voting 25–50% 2024-10-17 Ceased 2025-08-14
Ip2ipo Portfolio (Gp) Limited Corporate entity Shares 25–50%, Voting 25–50% 2019-09-16 Ceased 2023-01-01
Imperial Innovations Businesses Llp Corporate entity Voting 25–50% 2016-04-06 Ceased 2023-01-01

Filing timeline

Last 20 of 250 total filings

Material constitutional events — rename, articles re-file, resolution

  • 2025-11-21 MA Memorandum articles
  • 2025-11-21 RESOLUTIONS Resolution
Date Type Category Description
2026-02-24 CS01 confirmation-statement Confirmation statement with updates PDF
2026-01-22 PSC07 persons-with-significant-control Cessation of a person with significant control PDF
2025-12-24 PSC01 persons-with-significant-control Notification of a person with significant control PDF
2025-11-25 SH02 capital Capital alter shares subdivision
2025-11-24 SH10 capital Capital variation of rights attached to shares
2025-11-24 SH08 capital Capital name of class of shares
2025-11-21 MA incorporation Memorandum articles
2025-11-21 RESOLUTIONS resolution Resolution
2025-11-19 TM01 officers Termination director company with name termination date PDF
2025-11-19 TM01 officers Termination director company with name termination date PDF
2025-11-19 TM01 officers Termination director company with name termination date PDF
2025-10-07 AD01 address Change registered office address company with date old address new address PDF
2025-09-05 AA accounts Accounts with accounts type group
2025-05-06 SH01 capital Capital allotment shares PDF
2025-02-12 CS01 confirmation-statement Confirmation statement with updates PDF
2025-02-12 PSC01 persons-with-significant-control Notification of a person with significant control PDF
2025-02-12 PSC09 persons-with-significant-control Withdrawal of a person with significant control statement PDF
2025-02-12 SH06 capital Capital cancellation shares
2025-02-12 SH03 capital Capital return purchase own shares
2024-12-13 SH01 capital Capital allotment shares PDF

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
14

last 12 months

Capital events
7

last 24 months

Officers appointed
0

last 12 months

Officers resigned
3

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Year-on-year

FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31

Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers

Official Companies House page