AKAMIS BIO LIMITED
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Next accounts due
2026-09-30 (in 4mo)
Last filed for 2024-12-31
Confirmation statement due
2027-02-16 (in 9mo)
Last made up 2026-02-02
Watchouts
Cash
£13M
-22.9% vs 2023
Net assets
£11M
+10,428.5% vs 2023
Employees
30
-58.3% vs 2023
Profit before tax
-£2M
+81.8% vs 2023
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Material uncertainty over going concern
These circumstances represent a material uncertainty which may cast significant doubt on the group's and company's ability to continue as a going concern. Therefore, the group and company may be unable to realise their assets and discharge their liabilities in the normal course of business.
-
3 officer resignations in last 12 months
Multiple officers have left the board recently — see the People section for who.
-
1 PSC ceased in last 24 months
Significant control changed hands — see the Ownership section.
Name history
Renamed 2 times since incorporation
- AKAMIS BIO LIMITED 2023-01-03 → present
- PSIOXUS THERAPEUTICS LIMITED 2011-01-05 → 2023-01-03
- MYOTEC THERAPEUTICS LTD. 2006-11-17 → 2011-01-05
Net assets
2-year trend · vs Health Care median
Accounts
2-year trend · latest reflected 2024-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Turnover | £1,041,795 | £13,306,610 | |
| Operating profit | -£23,766,025 | -£2,039,420 | |
| Profit before tax | -£9,097,934 | -£1,652,478 | |
| Net profit | -£6,829,138 | -£1,130,058 | |
| Cash | £17,349,455 | £13,378,519 | |
| Total assets less current liabilities | £15,146,812 | £21,453,754 | |
| Net assets | £101,377 | £10,673,480 | |
| Equity | £101,377 | £10,673,480 | |
| Average employees | 72 | 30 | |
| Wages | £6,764,483 | £3,863,748 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Operating margin | -2281.3% | -15.3% | |
| Net margin | -655.5% | -8.5% | |
| Return on capital employed | -156.9% | -9.5% | |
| Gearing (liabilities / total assets) | 99.6% | 63.0% | |
| Current ratio | 2.42x | 3.77x | |
| Interest cover | -376.63x | -45.10x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Consolidated group
- Auditor
- PricewaterhouseCoopers LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Material uncertainty disclosed
“These circumstances represent a material uncertainty which may cast significant doubt on the group's and company's ability to continue as a going concern. Therefore, the group and company may be unable to realise their assets and discharge their liabilities in the normal course of business.”
Group structure
- AKAMIS BIO LIMITED · parent
- Hybrid Biosystems Limited 100%
- AkaBio US LegacyCo, Inc. 100%
Significant events
- “In February 2025, the Group announced the strategic decision to move its UK operations and related activities to the United States.”
- “On 9 December 2024, the Group entered into a license agreement with a new partner, to grant them the exclusive license to develop, manufacture and commercialise the viral vector developed from the T-Sign Platform technology.”
- “On 17 October 2024 the group raised additional funding through a Series A Prime Equity raise.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
2 active · 36 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| OAKWOOD CORPORATE SECRETARY LIMITED | Corporate Secretary | 2023-07-10 | — | — |
| DAVIS JR, Howard E | Director | 2022-07-01 | May 1973 | American |
Show 36 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| CAVALLA, David John, Dr | Secretary | 2007-09-23 | 2008-04-23 |
| HAROLD, Theodora | Secretary | 2008-04-23 | 2016-10-04 |
| KENNEDY, Madeleine | Secretary | 2016-10-04 | 2018-02-01 |
| MANDE, Priya | Secretary | 2018-02-01 | 2022-10-28 |
| RAYNER, William | Secretary | 2006-11-17 | 2007-09-24 |
| AGGER, Mette Kirstine | Director | 2012-07-06 | 2017-11-30 |
| AGGER, Mette Kristine | Director | 2012-07-06 | 2023-06-30 |
| BACH, Daniel | Director | 2018-02-01 | 2018-04-30 |
| BEADLE, John William, Dr | Director | 2009-05-21 | 2021-12-31 |
| BHAMAN, Maina | Director | 2010-04-09 | 2017-11-30 |
| BOWDEN, Christopher, Dr | Director | 2024-10-28 | 2025-11-12 |
| BOWDEN, Christopher, Dr | Director | 2023-06-01 | 2024-10-17 |
| BRAGMAN, Keith Stephen, Dr | Director | 2007-09-24 | 2009-01-16 |
| CAVALLA, David John, Dr | Director | 2007-09-23 | 2008-10-06 |
| CHAN, Adrian Kin Fei | Director | 2024-10-17 | 2025-11-12 |
| COATS, Andrew Justin Stewart, Professor | Director | 2007-09-24 | 2010-12-15 |
| COHEN, Ezra, Dr | Director | 2020-07-01 | 2023-09-30 |
| FOY, Matthew | Director | 2012-07-06 | 2024-10-17 |
| GARRAWAY, Richard, Dr | Director | 2006-11-17 | 2008-01-23 |
| GREDSTED, Lars | Director | 2023-06-30 | 2024-10-17 |
| HARRIS, Ralph Stephen | Director | 2008-04-23 | 2009-02-20 |
| HIGGONS, J. Duncan | Director | 2017-09-27 | 2024-10-17 |
| KERR, Simon Christopher | Director | 2009-03-16 | 2011-01-28 |
| L'HUILLIER, Phillip John, Dr | Director | 2010-12-15 | 2012-07-06 |
| LINCOLN, Robin Lewis | Director | 2021-02-24 | 2024-10-17 |
| MANDE, Priya | Director | 2016-09-29 | 2022-09-12 |
| MOORE, Michael, Dr | Director | 2009-05-21 | 2017-11-30 |
| PAOLETTI, Paolo, Dr | Director | 2011-11-23 | 2023-06-30 |
| POOLE WILSON, Philip, Professor | Director | 2007-09-23 | 2009-01-16 |
| ROWLAND JR, Charles | Director | 2017-09-27 | 2017-11-30 |
| ROWLAND JR, Charles | Director | 2017-09-27 | 2019-10-30 |
| SHEN, Richard Nan | Director | 2024-10-17 | 2025-11-12 |
| SWINGLAND, Charles Stuart Webb | Director | 2010-10-04 | 2017-11-30 |
| IP2IPO SERVICES LIMITED | Corporate Director | 2018-04-30 | 2024-10-17 |
| IP2IPO SERVICES LIMITED | Corporate Director | 2018-04-30 | 2018-04-30 |
| MERCIA FUND MANAGEMENT (NOMINEES) LIMITED | Corporate Director | 2010-12-15 | 2012-07-06 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Mr Howard E Davis Jr | Individual | Appoints directors | 2025-11-12 | Active |
| Dr Fengsheng Che | Individual | Voting 25–50% | 2024-10-17 | Ceased 2025-08-14 |
| Ip2ipo Portfolio (Gp) Limited | Corporate entity | Shares 25–50%, Voting 25–50% | 2019-09-16 | Ceased 2023-01-01 |
| Imperial Innovations Businesses Llp | Corporate entity | Voting 25–50% | 2016-04-06 | Ceased 2023-01-01 |
Filing timeline
Last 20 of 250 total filings
Material constitutional events — rename, articles re-file, resolution
- 2025-11-21 MA Memorandum articles
- 2025-11-21 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-02-24 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2026-01-22 | PSC07 | persons-with-significant-control | Cessation of a person with significant control | |
| 2025-12-24 | PSC01 | persons-with-significant-control | Notification of a person with significant control | |
| 2025-11-25 | SH02 | capital | Capital alter shares subdivision | |
| 2025-11-24 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-11-24 | SH08 | capital | Capital name of class of shares | |
| 2025-11-21 | MA | incorporation | Memorandum articles | |
| 2025-11-21 | RESOLUTIONS | resolution | Resolution | |
| 2025-11-19 | TM01 | officers | Termination director company with name termination date | |
| 2025-11-19 | TM01 | officers | Termination director company with name termination date | |
| 2025-11-19 | TM01 | officers | Termination director company with name termination date | |
| 2025-10-07 | AD01 | address | Change registered office address company with date old address new address | |
| 2025-09-05 | AA | accounts | Accounts with accounts type group | |
| 2025-05-06 | SH01 | capital | Capital allotment shares | |
| 2025-02-12 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-02-12 | PSC01 | persons-with-significant-control | Notification of a person with significant control | |
| 2025-02-12 | PSC09 | persons-with-significant-control | Withdrawal of a person with significant control statement | |
| 2025-02-12 | SH06 | capital | Capital cancellation shares | |
| 2025-02-12 | SH03 | capital | Capital return purchase own shares | |
| 2024-12-13 | SH01 | capital | Capital allotment shares |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 14
- Capital events
- 7
- Officers appointed
- 0
- Officers resigned
- 3
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.
Year-on-year
FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31
-
Turnover
+1,177.3%
£1,041,795 £13,306,610
-
Cash
-22.9%
£17,349,455 £13,378,519
-
Net assets
+10,428.5%
£101,377 £10,673,480
-
Employees
-58.3%
72 30
-
Operating profit
+91.4%
-£23,766,025 -£2,039,420
-
Profit before tax
+81.8%
-£9,097,934 -£1,652,478
-
Wages
-42.9%
£6,764,483 £3,863,748
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers