SYGNATURE DISCOVERY LIMITED
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Next accounts due
2026-12-31 (in 7mo)
Last filed for 2025-03-31
Confirmation statement due
2026-11-13 (in 6mo)
Last made up 2025-10-30
Watchouts
None on the register
Cash
£773K
-22.1% vs 2024
Net assets
£53M
-9.8% vs 2024
Employees
621
-7.2% vs 2024
Profit before tax
£3M
+47.9% vs 2024
Name history
Renamed 1 time since incorporation
- SYGNATURE DISCOVERY LIMITED 2011-09-07 → present
- SYGNATURE CHEMICAL SERVICES LIMITED 2004-08-19 → 2011-09-07
Net assets
2-year trend · vs Health Care median
Accounts
2-year trend · latest reflected 2025-03-31
| Metric | Trend | 2024-03-31 | 2025-03-31 |
|---|---|---|---|
| Turnover | £69,935,212 | £73,098,168 | |
| Operating profit | £6,708,404 | £5,616,886 | |
| Profit before tax | £2,152,876 | £3,184,758 | |
| Net profit | £620,879 | £2,633,396 | |
| Cash | £993,222 | £773,266 | |
| Total assets less current liabilities | £184,101,691 | £187,608,210 | |
| Net assets | £59,101,521 | £53,319,620 | |
| Equity | £59,101,521 | £53,319,620 | |
| Average employees | 669 | 621 | |
| Wages | £25,691,804 | £26,027,363 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2024-03-31 | 2025-03-31 |
|---|---|---|---|
| Operating margin | 9.6% | 7.7% | |
| Net margin | 0.9% | 3.6% | |
| Return on capital employed | 3.6% | 3.0% | |
| Gearing (liabilities / total assets) | 74.3% | 77.4% | |
| Current ratio | 1.92x | 2.23x | |
| Interest cover | 0.90x | 0.55x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Standalone (parent only)
- Auditor
- BDO LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“In auditing the financial statements, we have concluded that the Directors use of the going concern basis of accounting in the preparation of the financial statements is appropriate. Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the Company's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.”
Group structure
- SYGNATURE DISCOVERY LIMITED · parent
- Xenogesis Limited 100%
- Evergreen Holdco 3 Limited 100%
- Peak Proteins Ltd 100%
- FGHJ Limited 100%
- SB Drug Discovery Limited 100%
- Symmetry Calico Inc 100%
- Nuchem Sciences Inc 100%
Significant events
- “On 31st March 2025, SB Drug Discovery Limited transferred its trade and assets into Sygnature Discovery Limited and from that point, SB Drug Discovery Limited ceased to trade.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
4 active · 10 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| EDGAR, James Fenwick | Director | 2025-11-05 | May 1976 | British |
| HALL, Kieron Ashley | Director | 2025-11-05 | Mar 1972 | British |
| HIRST, Simon Christopher | Director | 2004-08-19 | Apr 1964 | British |
| JORDISON, Louisa Elizabeth | Director | 2021-11-01 | Oct 1978 | British |
Show 10 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| BOWNESS, Gillian | Secretary | 2009-08-28 | 2017-01-05 |
| HIRST, Barbara Anne | Secretary | 2004-08-19 | 2009-08-27 |
| TABINER, Victoria Jane | Secretary | 2017-01-05 | 2021-10-31 |
| CLEWLOW, Paul Jonathan, Dr | Director | 2009-04-01 | 2021-01-01 |
| EBBITT, Julie Anne | Director | 2004-08-19 | 2010-08-20 |
| NISBET, Louis Joseph, Dr | Director | 2013-07-01 | 2017-09-29 |
| OVERTON, Paul Douglas | Director | 2021-01-01 | 2024-05-20 |
| SLACK, John Alfred, Dr | Director | 2006-07-19 | 2017-09-29 |
| TABINER, Victoria Jane | Director | 2013-07-01 | 2021-10-31 |
| WILLIAMS, Jonathan Gareth | Director | 2008-10-01 | 2026-03-28 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Evergreen Holdco 1 Limited | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2017-08-01 | Active |
| Sygil Group Limited | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2016-04-06 | Ceased 2017-08-01 |
| Mr Simon Christopher Hirst | Individual | Significant influence | 2016-04-06 | Active |
Filing timeline
Last 20 of 127 total filings
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-16 | TM01 | officers | Termination director company with name termination date | |
| 2025-12-05 | AA | accounts | Accounts with accounts type full | |
| 2025-11-06 | AP01 | officers | Appoint person director company with name date | |
| 2025-11-06 | AP01 | officers | Appoint person director company with name date | |
| 2025-10-30 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-01-05 | AA | accounts | Accounts with accounts type full | |
| 2024-11-29 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-07-10 | TM01 | officers | Termination director company with name termination date | |
| 2024-04-12 | CH01 | officers | Change person director company with change date | |
| 2024-01-03 | AA | accounts | Accounts with accounts type full | |
| 2023-11-29 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2023-11-22 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2023-08-03 | SH01 | capital | Capital allotment shares | |
| 2023-07-27 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2022-12-15 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2022-12-07 | AA | accounts | Accounts with accounts type full | |
| 2022-11-28 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2022-06-10 | CH01 | officers | Change person director company with change date | |
| 2022-02-21 | RP04AR01 | annual-return | Second filing of annual return with made up date | |
| 2022-02-21 | RP04AR01 | annual-return | Second filing of annual return with made up date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 5
- Capital events
- 0
- Officers appointed
- 2
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.
Year-on-year
FY2024 → FY2025 · period ending 2025-03-31 vs 2024-03-31
-
Turnover
+4.5%
£69,935,212 £73,098,168
-
Cash
-22.1%
£993,222 £773,266
-
Net assets
-9.8%
£59,101,521 £53,319,620
-
Employees
-7.2%
669 621
-
Operating profit
-16.3%
£6,708,404 £5,616,886
-
Profit before tax
+47.9%
£2,152,876 £3,184,758
-
Wages
+1.3%
£25,691,804 £26,027,363
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers