TANGRAM THERAPEUTICS PLC
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Next accounts due
2026-07-31 (in 2mo)
Last filed for 2025-01-31
Confirmation statement due
2026-10-29 (in 5mo)
Last made up 2025-10-15
Watchouts
None on the register
Cash
£21M
-0.7% vs 2024
Net assets
£36M
+64% vs 2024
Employees
40
+14.3% vs 2024
Profit before tax
-£18M
-34.6% vs 2024
Name history
Renamed 4 times since incorporation — the current trading name was adopted 2025-09-18
- TANGRAM THERAPEUTICS PLC 2025-09-18 → present
- E-THERAPEUTICS PLC 2007-09-21 → 2025-09-18
- INROTIS TECHNOLOGIES LIMITED 2003-03-18 → 2007-09-21
- E-THERAPEUTIC SYSTEMS LIMITED 2001-11-13 → 2003-03-18
- CROSSCO (643) LIMITED 2001-10-15 → 2001-11-13
Net assets
2-year trend · vs Industrials median
Accounts
2-year trend · latest reflected 2025-01-31
| Metric | Trend | 2024-01-31 | 2025-01-31 |
|---|---|---|---|
| Turnover | £318,000 | — | |
| Operating profit | -£13,794,000 | -£18,646,000 | |
| Profit before tax | -£13,081,000 | -£17,609,000 | |
| Net profit | -£11,166,000 | -£14,869,000 | |
| Cash | £20,665,000 | £20,519,000 | |
| Total assets less current liabilities | £22,310,000 | £36,073,000 | |
| Net assets | £21,993,000 | £36,073,000 | |
| Equity | £21,993,000 | £36,073,000 | |
| Average employees | 35 | 40 | |
| Wages | £4,107,000 | £4,051,000 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2024-01-31 | 2025-01-31 |
|---|---|---|---|
| Operating margin | -4337.7% | — | |
| Net margin | -3511.3% | — | |
| Return on capital employed | -61.8% | -51.7% | |
| Gearing (liabilities / total assets) | 11.9% | 5.5% | |
| Current ratio | 8.87x | 17.26x | |
| Interest cover | -510.89x | -396.72x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Standalone (parent only)
- Auditor
- Crowe U.K. LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“At 31 January 2025, we reported cash and liquid resources and short-term investments of £32,723,000. The Board has prepared a detailed budget covering the forthcoming financial year, together with financial projections for the year thereafter. These support the view that the Company has sufficient cash to meet its operational requirements for at least 12 months from the signing of these financial statements.”
Significant events
- “During the last year, we successfully completed the cancellation of our admission to trading on AIM, effective 9 May 2024, following shareholder approval at our General Meeting on 29 April 2024.”
- “An equity fundraise of £28.9 million before expenses was completed in July 2024, by way of a subscription of funds managed by M&G Investment Management Limited and Richard Griffiths, both existing shareholders of the Company.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
6 active · 23 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BRETHERTON, Tim | Secretary | 2022-11-25 | — | — |
| BRETHERTON, Michael Anthony | Director | 2020-02-10 | Dec 1955 | British |
| JONES, Trevor | Director | 2015-10-28 | Aug 1942 | British |
| MORTAZAVI, Ahmad Ali | Director | 2020-02-10 | Jan 1971 | British,Iranian |
| PRIOR, David Gifford Leathes, Lord | Director | 2024-05-23 | Dec 1954 | British |
| PUNNETT, Jeremy | Director | 2024-07-16 | Sep 1973 | British,New Zealander |
Show 23 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| ANDRAS, Peter Emil, Dr | Secretary | 2004-10-05 | 2005-08-05 |
| CLARE, Sarah Collette | Secretary | 2020-02-28 | 2021-07-31 |
| DAWES, Christopher Charles Roland | Secretary | 2007-01-01 | 2007-10-05 |
| HOWSE, Nicholas Alan | Secretary | 2001-11-08 | 2004-10-05 |
| NICOLSON, Sean Torquil | Secretary | 2007-10-05 | 2017-02-28 |
| STEVEN, Susan Margaret | Secretary | 2017-03-15 | 2020-02-28 |
| DICKINSON DEES | Corporate Nominee Secretary | 2001-10-15 | 2001-11-08 |
| THE CITY PARTNERSHIP (UK) LTD | Corporate Secretary | 2005-08-05 | 2006-12-31 |
| VISTRA COMPANY SECRETARIES LIMITED | Corporate Secretary | 2021-08-01 | 2022-11-25 |
| BARLOW, Raymond John | Director | 2017-04-06 | 2020-02-10 |
| CARE, Timothy James | Nominee Director | 2001-10-15 | 2001-11-08 |
| CHOPRA, Rajesh, Dr | Director | 2012-02-03 | 2015-10-28 |
| CORDINER, Johnny Mark | Director | 2005-01-01 | 2011-06-10 |
| DRUCKER, Royston Frederick, Dr | Director | 2005-05-11 | 2010-09-08 |
| ELGER, Daniel William, Dr | Director | 2011-06-10 | 2014-04-07 |
| HOY, Bradley Richard | Director | 2008-09-04 | 2017-11-01 |
| JAMES, Oliver Francis Wintour, Professor | Director | 2007-10-05 | 2014-12-31 |
| MEDLICOTT, Steven | Director | 2014-04-07 | 2020-02-10 |
| NICOLSON, Sean | Director | 2015-04-01 | 2017-02-28 |
| ROSS, Iain Gladstone | Director | 2016-01-06 | 2020-02-10 |
| SELF, Stephen Raymond | Director | 2010-12-03 | 2016-09-30 |
| SODEN, Christine | Director | 2017-11-01 | 2020-02-10 |
| YOUNG, Malcolm Philip | Director | 2001-11-08 | 2016-07-12 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Invesco Ltd | Corporate entity | Shares 25–50%, Voting 25–50% | 2016-04-06 | Ceased 2019-10-28 |
Filing timeline
Last 20 of 253 total filings
Material constitutional events — rename, articles re-file, resolution
- 2025-09-18 CERTNM Certificate change of name company
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2025-10-24 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-09-18 | CERTNM | change-of-name | Certificate change of name company | |
| 2025-08-07 | SH01 | capital | Capital allotment shares | |
| 2025-06-06 | AA | accounts | Accounts with accounts type full | |
| 2025-01-23 | RP04SH01 | capital | Second filing capital allotment shares | |
| 2025-01-15 | SH01 | capital | Capital allotment shares | |
| 2024-10-15 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-08-08 | SH01 | capital | Capital allotment shares | |
| 2024-07-19 | AP01 | officers | Appoint person director company with name date | |
| 2024-07-10 | SH01 | capital | Capital allotment shares | |
| 2024-06-28 | AA | accounts | Accounts with accounts type full | |
| 2024-06-03 | AP01 | officers | Appoint person director company with name date | |
| 2024-02-06 | SH01 | capital | Capital allotment shares | |
| 2024-01-24 | SH01 | capital | Capital allotment shares | |
| 2023-10-16 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2023-09-21 | SH01 | capital | Capital allotment shares | |
| 2023-07-21 | SH01 | capital | Capital allotment shares | |
| 2023-05-26 | AA | accounts | Accounts with accounts type full | |
| 2023-04-22 | SH01 | capital | Capital allotment shares | |
| 2023-01-17 | SH01 | capital | Capital allotment shares |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 4
- Capital events
- 5
- Officers appointed
- 0
- Officers resigned
- 0
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.
Year-on-year
FY2024 → FY2025 · period ending 2025-01-31 vs 2024-01-31
-
Turnover
—
Not reported
-
Cash
-0.7%
£20,665,000 £20,519,000
-
Net assets
+64%
£21,993,000 £36,073,000
-
Employees
+14.3%
35 40
-
Operating profit
-35.2%
-£13,794,000 -£18,646,000
-
Profit before tax
-34.6%
-£13,081,000 -£17,609,000
-
Wages
-1.4%
£4,107,000 £4,051,000
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers