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Next accounts due

2026-09-30 (in 4mo)

Last filed for 2024-12-31

Confirmation statement due

2027-02-25 (in 9mo)

Last made up 2026-02-11

Watchouts

None on the register

Cash

£3M

+237.5% vs 2023

Net assets

£4M

-15% vs 2023

Employees

3

0% vs 2023

Profit before tax

-£5M

+63.5% vs 2023

Name history

Renamed 5 times since incorporation

  1. TIZIANA LIFE SCIENCES LIMITED 2021-11-01 → present
  2. TIZIANA LIFE SCIENCES PLC 2014-04-23 → 2021-11-01
  3. ALEXANDER DAVID INVESTMENTS PLC 2011-02-18 → 2014-04-23
  4. REGEN THERAPEUTICS PLC 1998-08-07 → 2011-02-18
  5. REGEN THERAPEUTICS PLC 1998-06-08 → 1998-08-07
  6. BIGBOOM PLC 1998-02-11 → 1998-06-08

Accounts

2-year trend · latest reflected 2024-12-31

Metric Trend 2023-12-312024-12-31
Turnover
Operating profit -£14,043,000-£5,097,000
Profit before tax -£13,664,000-£4,985,000
Net profit -£13,664,000-£1,178,000
Cash £874,000£2,950,000
Total assets less current liabilities £4,338,000£3,689,000
Net assets £4,338,000£3,689,000
Equity £4,338,000£3,689,000
Average employees 33
Wages

Values shown as filed in the company's annual accounts. indicates the figure wasn't present under that line item in that period. About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2023-12-312024-12-31
Return on capital employed -323.7%-138.2%
Gearing (liabilities / total assets) 52.5%59.7%
Current ratio 1.90x1.67x

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.

Audit & accounting basis

Accounting basis
FRS 101
Reporting scope
Standalone (parent only)
Auditor
PKF Littlejohn LLP
Audit opinion
Unqualified (clean)
Going concern
Affirmed

“Based on those Group projections, together with confirmation from the parent company that it will continue to make Group financial resources available to the Company, the directors conclude that the Company will be able to meet its liabilities as they fall due for the foreseeable future and therefore that it is appropriate to prepare the financial statements under the going concern basis of preparation.”

Significant events

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

5 active · 34 resigned

Name Role Appointed Born Nationality
OHS SECRETARIES LIMITED Corporate Secretary 2021-08-20
BRANCACCIO, John Patrick Director 2020-07-19 Mar 1948 American
CERRONE, Gabriele Marco Antonio Director 2014-04-24 Feb 1972 Italian
ELRIFI, Ivor Ramsay Director 2025-12-31 Jul 1961 American
SIMON, Willy Jules Director 2015-11-24 May 1951 Belgian
Show 34 resigned officers
Name Role Appointed Resigned
BEVERIDGE, Malcolm Charles Rhett Secretary 1999-05-20 2001-02-06
BOYD, Philip James, Dr Secretary 2014-04-24 2015-05-07
CARR, Brendan Michael Secretary 1998-03-05 1999-05-20
COOPER, Paul John Secretary 2015-05-07 2019-08-14
LOTT, Norman Alec Charles Secretary 2001-02-06 2014-04-24
ACCOMPLISH SECRETARIES LIMITED Corporate Secretary 2019-08-14 2021-08-20
HALLMARK SECRETARIES LIMITED Corporate Nominee Secretary 1998-02-11 1998-03-05
ADAMS, Thomas Henry Director 2021-02-01 2022-01-09
BEVERIDGE, Malcolm Charles Rhett Director 1998-03-05 2005-04-26
BOYD, Philip James, Dr Director 2014-04-24 2015-05-07
CARR, Brendan Michael Director 1998-03-05 1999-05-20
CORBIN, Keith Baden Director 1998-07-06 2008-07-09
DALLA-FAVERA, Riccardo, Dr Director 2014-04-24 2019-02-06
GARROD, Peter Redvers, Dr Director 2005-03-08 2011-02-18
GEORGDIADES, Jerzy Alexander, Doctor Director 1998-06-18 2002-09-02
GRATION, David Whitnall Director 1999-12-13 2002-11-29
GUTMANN, Andrew Director 2013-05-01 2015-01-22
HARVEY, Michael John Director 2000-02-23 2002-08-30
HICKS, Michael Director 2011-02-18 2013-05-01
LOMAX, Percy William Cecil Director 1998-06-12 2014-04-24
LOTT, Norman Alec Charles Director 1999-06-14 2013-05-01
MACRAE, Gregor Charles William, Mr. Director 2020-01-21 2020-06-18
MCGUIGAN, Christopher, Prof Director 2015-01-22 2016-03-11
MIROW, Gregor Kolumban Director 1999-01-11 1999-04-30
RENTSCHLER, Friedrich Erwin, Dr Director 1999-01-11 2001-04-30
ROURKE, Christopher William Director 2013-05-01 2014-04-24
SCOTT, David Alexander Hill Director 2011-02-18 2014-04-24
SHAILUBHAI, Kunwar, Dr Director 2015-01-22 2022-08-01
SHILTON, Timothy Simon Director 2002-12-10 2011-02-18
SMALL, Martin Jonathan Director 2002-12-10 2011-02-18
WOLF, Wieland Walter, Dr Director 1999-01-11 2002-01-15
ZAMBELETTI, Leopoldo Director 2018-04-04 2019-11-10
HALLMARK REGISTRARS LIMITED Corporate Nominee Director 1998-02-11 1998-03-05
HALLMARK SECRETARIES LIMITED Corporate Nominee Director 1998-02-11 1998-03-05

Ownership

Persons with significant control

Name Kind Nature of control Notified Status
Tiziana Life Sciences Limited Corporate entity Shares 75–100%, Voting 75–100%, Appoints directors 2021-10-21 Active
Graeme Walter Briggs Individual voting-rights-50-to-75-percent-as-trust, significant-influence-or-control-as-trust 2017-06-26 Ceased 2021-10-21

Filing timeline

Last 20 of 444 total filings

Date Type Category Description
2026-04-22 CS01 confirmation-statement Confirmation statement with no updates PDF
2026-03-03 AP01 officers Appoint person director company with name date PDF
2025-10-02 AA accounts Accounts with accounts type full
2025-02-11 CS01 confirmation-statement Confirmation statement with no updates PDF
2024-10-05 AA accounts Accounts with accounts type full
2024-04-12 RP04PSC07 persons-with-significant-control Second filing cessation of a person with significant control
2024-03-20 CS01 confirmation-statement Confirmation statement with no updates PDF
2024-03-20 PSC02 persons-with-significant-control Notification of a person with significant control PDF
2024-03-20 PSC09 persons-with-significant-control Withdrawal of a person with significant control statement PDF
2024-03-15 CH01 officers Change person director company with change date PDF
2023-10-13 AA accounts Accounts with accounts type full
2023-02-16 CS01 confirmation-statement Confirmation statement with no updates PDF
2022-11-09 AA accounts Accounts with accounts type full
2022-10-31 TM01 officers Termination director company with name termination date PDF
2022-03-14 CS01 confirmation-statement Confirmation statement with updates PDF
2022-03-11 CS01 confirmation-statement Confirmation statement with updates PDF
2022-02-08 TM01 officers Termination director company with name termination date PDF
2022-02-03 PSC08 persons-with-significant-control Notification of a person with significant control statement PDF
2022-02-01 PSC07 persons-with-significant-control Cessation of a person with significant control
2021-11-30 MISC miscellaneous Miscellaneous

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
3

last 12 months

Capital events
0

last 24 months

Officers appointed
1

last 12 months

Officers resigned
0

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Year-on-year

FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31

Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers

Official Companies House page